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    Computer model reveals NFL against the spread, over/under, money-line picks for each Week 1 matchup |

    - SportsLine's model evaluated the Week 1 NFL odds and revealed its NFL predictions, NFL score predictions and NFL betting picks for every game

    Top 5 Home

    1.

    imgCBS Sports

    Dolphins vs. Colts odds, predictions, bets: Proven model reveals free 2025 NFL Week 1 picks for Sunday

    2.

    imgCBS Sports

    LOOK: Florida State honors Ethan Pritchard for Week 2 game as freshman LB remains hospitalized after shooting

    3.

    imgCBS Sports

    Raiders vs. Patriots odds, predictions, bets: Proven model reveals free 2025 NFL Week 1 picks for Sunday

    4.

    imgClutchPoints

    Franz Wagner leads Germany into EuroBasket quarterfinals after dramatic late surge

    5.

    imgClutchPoints

    Trae Young hits Michigan with 'Oklahoma by 50' take

    6.

    imgCBS Sports

    2025 Week 1 NFL score predictions, odds, best picks today: Expert reveals exact scores for every game

    7.

    imgCBS Sports

    Brett Favre details 'scary' battle with Parkinson's, progression of disease after NFL career

    8.

    imgSBNation

    Max Verstappen clinches pole, and F1 history, at the Temple of Speed

    9.

    imgClutchPoints

    Oilers' Mattias Ekholm drops truth bomb ahead of final year of contract

    10.

    imgClutchPoints

    Tyrese Haliburton in the house for Iowa State-Iowa rivalry

    11.

    imgClutchPoints

    Penguins rumors: Pittsburgh 'open for business' as training camps loom

    12.

    imgClutchPoints

    Braves pitcher details Savannah Bananas journey after making MLB debut

    13.

    imgClutchPoints

    Texas QB Arch Manning connects with WR for 83-yard TD

    14.

    imgClutchPoints

    Felipe Lima vs. Daniel Marcos set for historic UFC Qatar Debut

    15.

    imgCBS Sports

    Week 1 NFL survivor pool picks, advice, strategy tips: NFL expert releases best knockout pick, teams to avoid

    16.

    imgCBS Sports

    Cardinals vs. Saints odds, prediction, bets: Proven model reveals free 2025 NFL Week 1 picks for Sunday

    17.

    imgClutchPoints

    Mariners get outfield boost amid postseason push

    18.

    imgClutchPoints

    Devils giving 4 veteran players professional tryouts

    19.

    imgClutchPoints

    Jaylon Johnson's injury status still unclear for Bears' season opener

    20.

    imgCBS Sports

    NFL longshot picks, Week 1 2025 odds, best props: This parlay brings a massive $4,000 return on a $10 bet

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