Seahawks vs. 49ers odds, prediction, bets: Advanced model reveals free 2025 NFL Week 1 picks for Sunday

https://sportshub.cbsistatic.com/i/2025/08/13/bbe2a9ef-444a-414c-9ec5-84a078c850aa/george-kittle-imagn-49ers.jpg

07/09/2025 18:48

The SportsLine projection model reveals its picks for the NFL Week 1 game between the San Francisco 49ers and the Seattle Seahawks

Top 5 Home

1.

Yesterday at 05:58

Lamar Jackson shoves Bills fan in retaliation after getting hit in head following Ravens TD vs. Buffalo

2.

Yesterday at 05:39

Why Keon Coleman was Dave Richard's breakout sleeper of 2025 and what his massive Week 1 means moving forward

3.

Yesterday at 06:01

Winners, Losers from Buffalo Bills' Clutch Comeback Win over Baltimore Ravens

4.

Yesterday at 06:16

Bills shocking win over Ravens ends with final score that's never been seen before in NFL history

5.

Yesterday at 06:47

Ravens QB Lamar Jackson explains why he didn't go bold first-down try vs. Bills